OpenClaw

variant-annotation

Query and annotate gene variants from ClinVar and dbSNP databases. Trigger when: - User provides a variant identifier (rsID, HGVS notation, genomic coordinates) and asks about clinical significance - User mentions "ClinVar", "dbSNP", "variant annotation", "pathogenicity", "clinical significance" - User wants to know if a mutation is pathogenic, benign, or of uncertain significance - User provides VCF content or variant data requiring interpretation - Input: variant ID (rs12345), HGVS notation (